The San Andreas star revealed the exciting news on his Instagram account, and took the opportunity to pay tribute to the "strong women" who have influenced him in his life.
Alongside an adorable snap of him cradling his beaming wife's baby bump, he wrote: "I was raised by and live with amazing and strong women, so the universe felt we needed one more... IT'S A BABY GIRL!!
"THANK YOU guys so much for the awesome support and love you've sent @laurenhashianofficial and myself from around the world.
"We're so grateful for this blessing and thrilled to share the news with y'all. #BringOnMoreEstrogenInOurHome #MeAndPuppyHobbsAreTheOnlyDudes #Proud2xPapaBear #JustOVerHereMakingBabiesAndStuff (sic)"
The announcement follows reports in September that the couple were expecting their first child together .
Dwayne is already father to Simone, 14, from his marriage to Dany Garcia, and he recently gushed about both his partner and daughter.
Speaking to Esquire, he said: "We do these stories and we talk so much about the business end, the success end, but then Lauren isn't mentioned and my daughter isn't mentioned.